Organic Chemicals
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High Quality Chinese Factory supply 3034-52-4 2-Chlorothiazole
- Molecular Formula: C3H2ClNS
- Molecular Weight: 119.575
- Vapor Pressure: 1.194mmHg at 25°C
- Melting Point: 85 °C
- Refractive Index: 1.571
- Boiling Point: 180.8 °C at 760 mmHg
- PKA: 0.84±0.10(Predicted)
- Flash Point: 63.155 °C
- PSA： 41.13000
- Density: 1.422 g/cm3
- LogP: 1.79650
2-Chlorothiazole(Cas 3034-52-4) Usage
InChI:InChI=1/C3H2ClNS/c4-3-5-1-2-6-3/h1-2H
3034-52-4 Relevant articles
INHIBITORS OF PROTEIN KINASES
-
Page/Page column 29, (2009/01/24)
The invention provides inhibitors of pro...
TYROSINE KINASE INHIBITORS CONTAINING A ZINC BINDING MOIETY
-
Page/Page column 56, (2008/06/13)
The present invention relates to tyrosin...
Cyclic protein tyrosine kinase inhibitors
-
Page 133, (2010/02/06)
Novel cyclic compounds and salts thereof...
Dehydroamino acids
-
, (2008/06/13)
Compounds of formula 1 and 1-1, wherein ...
3034-52-4 Process route
-
-
288-47-1
1,3-thiazole
-
-
3034-52-4
2-chlorothiazole
| Conditions | Yield |
|---|---|
|
1,3-thiazole;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.583333h;
With
trifluoroacetyl chloride;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
|
71%
|
|
With
n-butyllithium; trifluoroacetyl chloride;
In
tetrahydrofuran; hexane;
at -70 ℃;
for 0.5h;
|
87 % Spectr.
|
|
1,3-thiazole;
With
n-butyllithium;
at -70 ℃;
With
tetrachloromethane;
In
tetrahydrofuran;
at -70 ℃;
for 0.5h;
|
90 % Chromat.
|
-
-
96-50-4
2-thiazolylamine
-
-
3034-52-4
2-chlorothiazole
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; sodium chloride; sodium nitrite;
In
water;
at 20 ℃;
for 1h;
|
45%
|
|
|
|
|
|
3034-52-4 Upstream products
-
141305-44-4
thiazole 3-oxide
-
288-47-1
1,3-thiazole
-
7647-01-0
hydrogenchloride
-
96-50-4
2-thiazolylamine
3034-52-4 Downstream products
-
4175-70-6
2-(piperidin-1-yl)thiazole
-
42270-37-1
1-thiazol-2-yl-piperazine
-
104396-29-4
(3-methoxy-phenyl)-thiazol-2-yl-acetonitrile
-
874509-08-7
[4-(4-nitro-benzenesulfonyl)-phenyl]-thiazol-2-yl-amine
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