Pharmaceutical

Methyl 4-bromobenzoate

  • CAS:619-42-1
  • purity:99%
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Good factory exports good Methyl 4-bromobenzoate 619-42-1

  • Molecular Formula: C8H7BrO2
  • Molecular Weight: 215.046
  • Appearance/Colour: White crystals or crystalline powder 
  • Vapor Pressure: 0.0111mmHg at 25°C 
  • Melting Point: 77-81 °C(lit.) 
  • Refractive Index: 1.549 
  • Boiling Point: 262.2 °C at 760 mmHg 
  • Flash Point: 112.4 °C 
  • PSA: 26.30000 
  • Density: 1.498 g/cm3 
  • LogP: 2.23570 

Methyl 4-bromobenzoate(Cas 619-42-1) Usage

Purification Methods

Crystallise the ester from MeOH. EtOH (m 81o, also 80.5o, 79.5o) or *C6H6/pet ether (m 78-79o). [Beilstein 9 H 352, 9 III 1405, 9 IV 1017.]

General Description

Methyl 4-bromobenzoate is a para-substituted aryl bromide. Mol-ecules of methyl 4-bromobenzoate are almost planar. The compound is isostructural with methyl 4-iodo-benzoate. The Zeeman effect on the N.Q.R. (nuclear quadrupole resonance) of methyl 4-bromobenzoate on single crystals, has been investigated by the ′geometric method′.

InChI:InChI=1/C8H7BrO2/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5H,1H3

619-42-1 Relevant articles

The tremulanes, a new group of sesquiterpenes from the aspen rotting fungus Phellinus tremulae

Ayer,Cruz

, p. 7529 - 7534 (1993)

A series of new sesquiterpenes, the trem...

The Highly Effective Cobalt Based Metal–Organic Frameworks Catalyst for One Pot Oxidative Esterification Under Mild Conditions

Chindawong, Chakkresit,Mekrattanachai, Pagasukon,Setthaya, Naruemon,Song, Wei Guo,Zhu, Lei

, (2021/08/03)

The cobalt-based metal organic framework...

Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives

Bernard, Josephine,Capilato, Joseph N.,Hoy, Erik P.,Mattiucci, Joseph,Pellegrinelli, Peter J.,Perez, Lark J.,Philippi, Shane,Schnorbus, Logan

supporting information, p. 5298 - 5302 (2021/06/30)

The development of a novel acetyl nitrat...

Method for preparing carboxylic ester compounds by oxidizing and breaking carbon-carbon bonds of secondary alcohol compounds

-

Paragraph 0056-0057; 0092, (2021/06/02)

The invention discloses a method for pre...

Br?nsted acid-catalyzed chlorination of aromatic carboxylic acids

Yu, Zhiqun,Yao, Hongmiao,Xu, Qilin,Liu, Jiming,Le, Xingmao,Ren, Minna

, p. 685 - 689 (2021/04/09)

The chlorination of aromatic carboxylic ...

619-42-1 Process route

methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

1.4-dibromobenzene
106-37-6

1.4-dibromobenzene

1,4-benzenedicarboxylic acid dimethyl ester
120-61-6

1,4-benzenedicarboxylic acid dimethyl ester

terephthalic acid
100-21-0

terephthalic acid

4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

Conditions
Conditions Yield
With tert-Amyl alcohol; sodium hydride; cobalt(II) acetate; In tetrahydrofuran; at 40 ℃; for 14h; under 760 Torr; Irradiation;
6%
12%
80.5%
carbon monoxide
201230-82-2

carbon monoxide

1.4-dibromobenzene
106-37-6

1.4-dibromobenzene

1,4-benzenedicarboxylic acid dimethyl ester
120-61-6

1,4-benzenedicarboxylic acid dimethyl ester

terephthalic acid
100-21-0

terephthalic acid

4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

Conditions
Conditions Yield
With methanol; tert-Amyl alcohol; sodium hydride; cobalt(II) acetate; In tetrahydrofuran; at 40 ℃; for 14h; under 760 Torr; Irradiation;
80.5%
12%
6%

619-42-1 Upstream products

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    Ethyl 4-bromobenzoate

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    4-chlorobenzoyl chloride

619-42-1 Downstream products

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    methyl 4-(4-phenoxyphenoxy)benzoate

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    methyl 4-phenoxybenzoate

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