What is the 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone?

5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone is , while it's Molecular Formula is C17H14 O6. Scutellarein-6,4''-dimethyl ether (CAS# 520-12-7) is a flavonoid isolated from South African weed Chromolaena odorata (Asteraceae) having pharmacological activity against uropathogens.

What is the 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone?

5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone is , while it's Molecular Formula is C17H14 O6. Scutellarein-6,4''-dimethyl ether (CAS# 520-12-7) is a flavonoid isolated from South African weed Chromolaena odorata (Asteraceae) having pharmacological activity against uropathogens.

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5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone

Q: What is the CAS number for 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone?

The CAS number of 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone is 520-12-7.

CAS：520-12-7
purity：99%

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Factory supply good quality 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone 520-12-7 with stock

Molecular Formula: C17H14 O6
Molecular Weight: 314.295
Vapor Pressure: 2.15E-13mmHg at 25°C
Melting Point: 220-223°
Boiling Point: 565.5°Cat760mmHg
PKA: 6.49±0.40(Predicted)
Flash Point: 212.3°C
PSA： 89.13000
Density: 1.402g/cm³
LogP: 2.88840

5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone(Cas 520-12-7) Usage

Definition

ChEBI: A dimethoxyflavone that is the 6,4'-dimethyl ether derivative of scutellarein.

InChI:InChI=1/C17H14O6/c1-21-10-5-3-9(4-6-10)13-7-11(18)15-14(23-13)8-12(19)17(22-2)16(15)20/h3-8,19-20H,1-2H3

520-12-7 Relevant articles

-

Smirnova et al.

, (1973)

-

Kuptsova,Ban'kovskii

, (1970)

Pubescidin, an isoflavone glycoside from Centrosema pubescens

Tostes, Joao B. F.,Da Silva, Antonio J. R.,Parente, Jose P.

, p. 1069 - 1072 (1997)

A new isoflavone glycoside, irisolidone ...

-

Smirnova et al.

, (1974)

Semi-synthesis of a series natural flavonoids and flavonoid glycosides from scutellarin

Ding, Ning,Li, Yingxia,Wang, Yujie,Xiao, Qiang,Xie, Mingxian,Yan, Shiqiang

, (2020/01/22)

Natural flavonoids and flavonoid glycosi...

Synthesis and biological evaluation of methylated scutellarein analogs based on metabolic mechanism of scutellarin in vivo

Shi, Zhi-Hao,Li, Nian-Guang,Wang, Zhen-Jiang,Tang, Yu-Ping,Dong, Ze-Xi,Zhang, Wei,Zhang, Peng-Xuan,Gu, Ting,Wu, Wen-Yu,Yang, Jian-Ping,Duan, Jin-Ao

, p. 95 - 105 (2015/11/10)

Scutellarin (1) could be hydrolyzed into...

In vitro biological evaluation of novel 7-O-dialkylaminoalkyl cytotoxic pectolinarigenin derivatives against a panel of human cancer cell lines

Bonesi, Marco,Tundis, Rosa,Deguin, Brigitte,Loizzo, Monica R.,Menichini, Federica,Tillequin, Francois,Menichini, Francesco

body text, p. 5431 - 5434 (2009/05/30)

The effect of novel pectolinarigenin der...

Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

-

, (2008/06/13)

PCT No. PCT/KR97/00144 Sec. 371 Date Jan...

520-12-7 Process route

: 1447-88-7
hispidulin

: 74-88-4
methyl iodide

: 6601-62-3
salvigenin

: 520-12-7
pectolinarigenin

Conditions

Conditions	Yield
With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 6h; Inert atmosphere;	38% 49%

: 27740-01-8,676536-34-8
scutellarin

: 6601-62-3
salvigenin

: 520-12-7
pectolinarigenin

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1: hydrogenchloride / water; ethanol / 36 h / Inert atmosphere; Reflux 2: diphenylether / 0.5 h / 175 °C / Inert atmosphere 3: potassium carbonate / N,N-dimethyl-formamide / 0 - 25 °C / Inert atmosphere 4: acetic acid / water / 1.5 h / Inert atmosphere; Reflux 5: potassium carbonate / N,N-dimethyl-formamide / 0 - 25 °C / Inert atmosphere 6: potassium carbonate / N,N-dimethyl-formamide / 12 h / 25 °C / Inert atmosphere 7: hydrogen; palladium 10% on activated carbon / ethanol; tetrahydrofuran / 8 h / 760.05 Torr 8: potassium carbonate / N,N-dimethyl-formamide / 6 h / 25 °C / Inert atmosphere With hydrogenchloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; acetic acid; In tetrahydrofuran; diphenylether; ethanol; water; N,N-dimethyl-formamide;

Yield

Multi-step reaction with 8 steps

1: hydrogenchloride / water; ethanol / 36 h / Inert atmosphere; Reflux

2: diphenylether / 0.5 h / 175 °C / Inert atmosphere

3: potassium carbonate / N,N-dimethyl-formamide / 0 - 25 °C / Inert atmosphere

4: acetic acid / water / 1.5 h / Inert atmosphere; Reflux

5: potassium carbonate / N,N-dimethyl-formamide / 0 - 25 °C / Inert atmosphere

6: potassium carbonate / N,N-dimethyl-formamide / 12 h / 25 °C / Inert atmosphere

7: hydrogen; palladium 10% on activated carbon / ethanol; tetrahydrofuran / 8 h / 760.05 Torr

8: potassium carbonate / N,N-dimethyl-formamide / 6 h / 25 °C / Inert atmosphere

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; acetic acid; In tetrahydrofuran; diphenylether; ethanol; water; N,N-dimethyl-formamide;